




Background: Originally thought to be purely due to LV diastolic dysfunction, studies in western countries have suggested that heart failure with preserved ejection fraction (HFpEF) is more complex. In patients with HFpEF, LV systolic function is commonly considered normal …
Apr 29, 2020 · Introduction The pathophysiology of heart failure with preserved ejection fraction (HFpEF) remains incompletely defined. We aimed to characterize HFpEF compared to heart failure with reduced ejection fraction (HFrEF) and asymptomatic hypertensive or non-hypertensive controls. Materials and methods Prospective, observational study of 234 subjects (HFpEF n = 140; HFrEF n = 46, controls n = …
Assessing LV Systolic Function: From EF to Strain Analysis ...
Oct 13, 2020 · The following are key points to remember about this article on assessing left ventricular (LV) systolic function: from ejection fraction (EF) to strain analysis: LVEF, defined as the ratio of LV stroke volume to LV end-diastolic volume, is one of the most …Nearly half of patients with heart failure (HF) in the community have HF with preserved ejection fraction (HFpEF) and mortality and morbidity in this group of patients is high. 1–4 However, to date, there is no established pharmacotherapy to improve survival in HFpEF. 5–9 Patients with HFpEF are often elderly and their primary chronic symptom is severe exercise intolerance, which results ...
There is an emerging interest in heart failure with preserved ejection fraction (HFPEF) because of its high preva- ... As a method of preserved lv function heart assessing diastolic function, the invasive measurement of LV pressure is the gold standard, but is not practical. Pulsed Doppler transmitral flow velocity curves
Methods: Among TOPCAT (Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist Trial) participants, we performed latent-class analysis to identify HFpEF phenogroups based on standard clinical features and assessed differences in multiple biomarkers measured from frozen plasma; cardiac and arterial structure/function ...
Nearly half of patients with heart failure (HF) in the community have HF with preserved ejection fraction (HFpEF) and mortality and morbidity in this group of patients is high.[1–4] However, to date, there is no established pharmacotherapy to improve survival in HFpEF.[5–9] Patients with HFpEF are often elderly and their primary chronic symptom is severe exercise intolerance, preserved lv function heart which results ...
LV Mechanical Dyssynchrony in Heart Failure With Preserved ...
dyssynchrony in heart failure with preserved ejection fraction (HFPEF) complicating acute coronary syndrome (ACS). BACKGROUND In systolic heart failure, LV mechanical dyssynchrony worsens cardiac function and cardiac resynchronization therapy improves clinical outcome. The role of LV mechanical dyssynchrony in HFPEF complicating ACS is unknown.Abstract. Aims: Mechanical dyssynchrony has been reported in heart failure with preserved ejection fraction (HFpEF), with a majority of patients having a narrow QRS complex; however, whether any benefit is observed with restoration preserved lv function heart of dyssynchrony remains unclear. We sought to assess left ventricular (LV) dyssynchrony and function in HFpEF and elucidate the underlying mechanisms that may ...
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